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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1295bfac86a3143d50e59dd9e7c0941ed1238ca3b5dd789d03be510e6bc0542b' 
  AND token = '0H9R2NHK2EQ5QbDqf49eFoJghpTZbDMd5lPVaBUuyto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}