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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eab4b3d81a6be973e50a4acee1e6e9343b89ffcd9671a646f627b48547eaa7ff' 
  AND token = 'wD7Pdi/PxHNn6w5UnlJbBqw3PU3cpDDUHKmMfNZd+Xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}