SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6f6a78aba3a047831caf17634c37fa78f26aaee968a7fd6e2c09f7bcf87cc98' 
  AND token = '8NPv4zFaLhgs8xRdYwfHwwN4gb5dBrttcqfwE9W7RaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}