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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bd49c102faf00642d6e9c527879449b2c105a467cc9914b90726745014dc692' 
  AND token = 'OcAET4vGe+OD5SFsh47XwU0zl1+6YzGxha44Sgj0oEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}