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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bcb3b69e90bf13645084a36d10dc22b6763d5e2165fd068ee38f93f8d34e39d' 
  AND token = 'X1t3b/l5G1InUUYGwuK5n2CGuqYwZrHAS3y118nEv8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}