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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9630184763f3cc068cbb15f9fb709e00d56e3587e7b3dc07334f7e51620a4d8' 
  AND token = 'yxGUKAcNdCdeORVet1GO/P+Ap1RMF0K5bKTYB9kuf7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}