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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e82ee180a7170ca2e70c523781de51edf94e0e1a00c286248be1373137d3627' 
  AND token = 'K+wH15zl0XaiTatZxt8tpsAbIxzcc57esuoPYjvaqPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}