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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dc672fc0a1ddf43a27c97aab74b1f659bb854904707d812b01844df55de349a' 
  AND token = 'OFqN7P/Y5UUAbDhft37fXdRQkJLGUc885lLvARkgeyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}