SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd37620c9ec9d6059f44137465d15dc9671dbec80895aec9690687831030de4e5' 
  AND token = 'GskOUfR2DsUMK5JKnOY3PvAyIWVZY6KcE1ca5ZjBuPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}