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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8caee1fd43055483e8bf67fcc4e6fd618bc1067eb39036f274bad761828549ac' 
  AND token = 'J5al8kfUVdn9Qejm7dB/5tUINqcBxOmwcmUdWks5NpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}