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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44ee60abd0f602d9c292cce955d5495e16fe61863b43a6b58a635cb4a02f8d9f' 
  AND token = 'qiSS5twKu8F4W5FCF325iH7oSmKD7S0ZbYewpjm7T48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}