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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41cb05a93545cc665f84848265463a6d2ef736b519515ca085028f16d41fa18a' 
  AND token = 'QPRPdY+Ca8hDwZu+79Q3GtzwMIkfl7ynYBkfMJ2wQcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}