SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24dbf00fe3cb3405fe81f639433d24ba54fa42ca73c4274f3504f6a2b321304b' 
  AND token = '2atQsdBpNqOu4bIpPd5tcbLB41SZhbhrG1lvqHmrhTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}