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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b3901081f34e6c6c672ef3fc8ce4d173ef37f409ee03360bb8684bddca2a7de' 
  AND token = '6D8X/r+mpbBVrZdm1ouGi/QX3I4Y0CcVadXm17crjfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}