SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3ec721ef01b2e0b4b6813c64eb627de94f3a9a32e86df58d1f21d05f05bc98b' 
  AND token = 'l7eIun7yb6oHKn+VZz7xYUU2HSDmNqW8H4FtXaNYwv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}