SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e7674edc70ae783fc2f7385e0b6dec0f2616e32bfcafb15af965015954ec342' 
  AND token = '3H+u0lZ0rjpXBuhtvb6JK790TfCfzuge2Z7wHZMDo/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}