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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f9a3299d8bd0178ade84c6229cf155f197e6406d08eb7c628569b12edd77157' 
  AND token = 'BM+CZkab78KuYTLYp1yNqmzzJ1FG9rxqGKWxTAff4C0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}