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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50b1a394c660c7a594528def70792866c2a15f2313c5d2de85f490936f413b4c' 
  AND token = 'Z6e45HcLafl/QPMUlZTCnQZSUxi6lRpkdkRxeFjvWms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}