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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4da44974d656d189368dac8733666080a2051f41d3720f96cd10c1bf2a098f4d' 
  AND token = 'ZJJAm9TMwxEWE4z/C1M9D96k0+K9PB0CudvxJGrDavI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}