SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44d9a4ab95f7334262a870d0acd599bf1e05f3e12df55068edd2a0096e5262a5' 
  AND token = '4a4q5TJz4YA6qlzn6wuVgmeYFGWS0+rMkBvfi6HHNcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}