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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b357ce22c2faafee1d98fe0a7a6777ca3f1d883030e60c2c7011379cfd280946' 
  AND token = 'BDR+Ik4Nsrr7sLehlX+RJEDV9rKpZJiC7GkizQajFxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}