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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f081819804893dfdc9754f57e7161ecef6655f8f72bf9fd8693334a7013adb11' 
  AND token = 'PsshKfIW6AAvAjfT73WcZFAPuV+zeYaxSdWRKBuWAiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}