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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0de8ba1e2fc9406675363e70ed2da73608b29a434bb43c9ee3d2a701c08ad9bc' 
  AND token = 'ooJdFN4a/2bLmv+Ic9+1D02NDVIspJsCscNMQS0YvzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}