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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40473e0a598c3ad764d616183abdd04842f9f0c6862d0e9755dcff523f346176' 
  AND token = '74YAC57+xWq5ix2SxW4cV+BdyuCJYVMgfv6DSmmOvqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}