SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3de9a4ce094f9aa24f69b647f191b6c33708f7602b22088c5007c866b56bb905' 
  AND token = 'YMN2VqW0sXhaP5KV+q9alGSD1X+9XfqopqvMTo5I1Aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}