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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd78bda243ab359dcad015f0a7d2c1b21550fd2196735304f7ddb91524b6a6b2a' 
  AND token = 'bUSd9y/CmAOenACp4YudDuWZtRNpm6oRX6CyHFAtemc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}