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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c108bb4cadcc904a5c3c728267c72bb40e3ff711f433e8ba68941d484deb274' 
  AND token = 'QAvWtdBkl6aJ1XeeM6NeSJG2PPR4BzH0Q/vaFvYE5as=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}