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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c0ab3943758fa54dade3abc70987f8a69cf5f5e742fbaefe02f24f7982813ed' 
  AND token = 'JXSjN21f1BRW8GKUbMVOLc09p/LCqFcvZmR9dijb0h8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}