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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee6e761666fcd6251b46c1a2c8d195b4736b8d6111b8858cb2733522cab05c48' 
  AND token = 'Nmo/HmbeTYZKSqiuyQ3umcMHfIYsFBHVCewyPVgYIic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}