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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de8a5a596347dda300f8d131e79e8d092f6afeffad560cd3e14b5bb016da3c72' 
  AND token = 'OqhV+dmcsOLkfDMV7owgL9mOcn5/FavMDQJx9mgPHuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}