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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a2d3d5723023dee42034935ed2e6588f8ccb1686356576cece3246f970a27bf' 
  AND token = 'WpphxxLk0MdAExLWm42o0MP4bY1G0G02lgFLqxfL7Eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}