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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '182af445fbc4e1842627a215dc67e075e5f889f794a37678d99c2e033b4d4b25' 
  AND token = 'MICgwe93X3XnFStCQS8L1SOjviBKfUpIR5ya6ZBb9ug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}