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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a8357252f0a14c2bf4fc364eaf19009aeb0e3340be2e059350bf7c76222eaa3' 
  AND token = 'hoZKuMspbSvgxyM2CJYeT10iFNezUP1Q+/vLc/tn5QM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}