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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6c9404be703b6d0ee7ad45fc385f18184b8f456e85a4ae494e838b4ab16eac9' 
  AND token = 'uUPjNGkibRuq28D9qdoAwJYUoqr/FeJvAWti53r7zjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}