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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72b3421fc1c90436deb9cb8bfe05af3da906966121969634cab5f0bfe24ef978' 
  AND token = 'IgwDm/b7N8kz4O8eicitwP7Heng9no+AJfCpQHNh3go=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}