SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e098a2cca129b57d27dac5b90bfc218ea02f2df5d04379edaca111b6311bb6e0' 
  AND token = 'B1XkRpods3uvJuyFpGAV95WSwLgnkDMLXTI9x9mss+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}