SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b27e53a1499add13f483a10b403d6d7f8db34d2bda0aad9cddebabd73d80c33' 
  AND token = 'dge2fX3MPvuL9R/UotyUd/uASgSDUG++lkXhXwAAc04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}