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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b562b377dc750bc1a49a844eea7e2c07c121982c8c126ffbf65476b553ba4804' 
  AND token = 'LPnC7i+N1S1kgwqbrlyRIlv4cpKmfGxjGbRtPXl25Tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}