SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f751608c34fd73e284e92cf637aed78d776525892e39d1eb175d87aae0c7d5f' 
  AND token = 'kk9OBL3RItRiq4q16bwhaBEhdD2Y9buqBOX76vdFNvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}