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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72fef67b20f1f3c7c56b9dd7be589b48c6bf2ab89e4a8884d961710b9d76e783' 
  AND token = 'yFDYuuafitiwa2zA3YHphm9hFf52+aFm+sWgYzAGsmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}