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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4067aca5f4c7b81e092c282dfd7065b4c7a2260c3b823cfa870b135a509f440' 
  AND token = 'kWqmeaDkkVo1CJk+aeVmG5HrjVjC2ml+evoX8o+3TTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}