SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '644c694099479466299c101516619ae69e6fb144ff29cadafdb66cc2596a640e' 
  AND token = 'vlrzpSFEwvZucD0OWbJLp3NZrtA3f3YWlqL046MZLL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}