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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0965e66ba0c3e2a21d6a2557f021c94bfca3876648f3811278523a6853e0e6c' 
  AND token = '53siZNov2N8bdOa0gZCGgiorUiTdXJspTV4u0j9r4WY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}