SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b236be8399f414cc2e27a1bd491bbc13cde910c7f4f6dcbf1b8f41e6f97a25c' 
  AND token = 'Ri+K4DSaP5M/1jEzyHrVcmfciadr+M12bjZ87rJT5Wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}