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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4e3fd05b8bb541a0d96aa54f01392edd380b0a6d72bf0fb8add27711a6ae660' 
  AND token = 'F0btf1EChsqNM2HtnaRayPm7bLvm/WuehJ8uD+NpcqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}