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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37a760027eb5a8988cb24564ec932e0ea7773d14b9355501a0035eb1e864ca18' 
  AND token = '2GrV8tAdDsFSJ7kYN+jqImgGBkM23GG1nqBOvQMA6uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}