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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a721a0537be185f42eb53df9ccbddb55977636e2a67446cb8bf9f478add7da50' 
  AND token = 'T1J3671f6wbmwO1ZqWtptJ6krEYyn4TFxMGhkoL3wio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}