SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a72f635e8dac72fd20929d528b425d3b1ab20601fcc6130bfb9432fd1d0e749' 
  AND token = 'qkYuCjyoTXmKwfD13Xlv8fwfCcCNnwNQXr4Jv7N1tC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}