SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dea5ade5dd9832ce48afd414a0f536272425c6abd980d1fe8af6abdc30541a59' 
  AND token = 'AHliYWfR0aMsNqzHnKKW6eh1GI869zHbhiVuiOSp/jE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}