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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0d026c50308be3d3b5fabd9f2205b945f2e73c101d1c2b99ac6232e0827eb02' 
  AND token = '6Qn7DSwcH5bqD8e7nw+/1YK23I0TgpJii/T7HpBLcMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}